APC-B*07:02/Human SBF1 (RPYSNVSNL) MHC Tetramer (CAT#: MHC-LC2103)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human SBF1 of peptide RPYSNVSNL covering 1581-1589 and B*07:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to nuclear bodies.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74004/1469_G7_1_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to nuclear bodies.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74004/1469_G7_1_selected.jpg
Figure 2 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100241-SBF1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100241-SBF1
Specifications
- Allele
- B*07:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- SBF1
- Antigen Species
- Human
- Peptide
- RPYSNVSNL
- Range
- 1581-1589
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the protein-tyrosine phosphatase family. However, the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket. This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation. Mutations in this gene have been associated with Charcot-Marie-Tooth disease 4B3. Pseudogenes of this gene have been defined on chromosomes 1 and 8. [provided by RefSeq, Dec 2014]
- Alternative Names
- SBF1; Myotubularin-related protein 5; MTMR5; CMT4B3; DENND7A
- Gene ID
- 6305
- UniProt ID
- O95248
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MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC2102 | PE-B*07:02/Human SBF1 (RPYSNVSNL) MHC Tetramer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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