This product is a recombinant Human antibody that can recognize C. difficile TcdA. PA50 is a humanized mAb with both potent and broad-spectrum neutralizing activity. PA50 is able to specifically recognize a repeating epitope within the CROPs domain of TcdA.
Figure 2 Neutralization of purified toxins by murine and humanized monoclonal antibodies (mAbs).
Humanized PA-50 and murine PA-50 (mPA-50) were compared for neutralization of purified toxin A on T-84 cells.
Marozsan, A. J., Ma, D., Nagashima, K. A., Kennedy, B. J., Kang, Y., Arrigale, R. R., ... & Olson, W. C. (2012). Protection against Clostridium difficile infection with broadly neutralizing antitoxin monoclonal antibodies. The Journal of infectious diseases, 206(5), 706-713.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
PFBC-481 | Recombinant Human Anti-C. difficile TcdA Antibody Fab Fragment (PA50) | ELISA, Neut | Human Fab |
HPAB-0659YY-F(E) | Human Anti-C. difficile TcdA Recombinant Antibody (clone PA-50-YTE); Fab Fragment | FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBC-481 | Recombinant Human Anti-C. difficile TcdA Antibody scFv Fragment (PA50) | ELISA, Neut | Human scFv |
HPAB-0659YY-S(P) | Human Anti-C. difficile TcdA Recombinant Antibody (clone PA-50-YTE); scFv Fragment | FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0659YY | Human Anti-C. difficile TcdA Recombinant Antibody (clone PA-50-YTE) | FuncS | Human IgG |
There are currently no Customer reviews or questions for PABC-481. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.