Human Anti-HIV-1 gp120 Recombinant Antibody (clone L17) (CAT#: FAMAB-0056WJ)

This product is a human monoclonal antibody targeting Human Immunodeficiency Virus Type 1 gp120. This antibody is derived phage display libraries.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
ELISA

Figure 1 Binding of Fab ANA15 (5 gml), donor serum (patient with Felty's syndrome, 1:200), polyclonal rabbit anti-human eEF1A-1 antibody (1:200), anti-gp120 Fabs L17 (negative control, 5 gml) to purified intact rabbit eEF1A-1 by ELISA.

Figure 1 Binding of Fab ANA15 (5 gml), donor serum (patient with Felty's syndrome, 1:200), polyclonal rabbit anti-human eEF1A-1 antibody (1:200), anti-gp120 Fabs L17 (negative control, 5 gml) to purified intact rabbit eEF1A-1 by ELISA.

To evaluate specificity, Fab ANA15 was also tested for binding to ovalbumin, HIV-1 gp120, and RNA. Ditzel et al.

Ditzel, H. J., Masaki, Y., Nielsen, H., Farnaes, L., & Burton, D. R. (2000). Cloning and expression of a novel human antibody–antigen pair associated with Felty's syndrome. Proceedings of the National Academy of Sciences, 97(16), 9234-9239.

ELISA

Figure2 Analysis of binding of Fab ANA15, polyclonal rabbit anti-human eEF1A-1 antibody, and anti-gp120 Fab L17 (negative control) to the different purification fractions (as shown in A) by using ELISA.

Figure2 Analysis of binding of Fab ANA15, polyclonal rabbit anti-human eEF1A-1 antibody, and anti-gp120 Fab L17 (negative control) to the different purification fractions (as shown in A) by using ELISA.

Strong reactivity of Fab ANA15 and rabbit anti-human eEF1A-1 with the purified eEF1A-1 fragment, but no reactivity with the flow-through was observed.

Ditzel, H. J., Masaki, Y., Nielsen, H., Farnaes, L., & Burton, D. R. (2000). Cloning and expression of a novel human antibody–antigen pair associated with Felty's syndrome. Proceedings of the National Academy of Sciences, 97(16), 9234-9239.


Specifications

  • Host Species
  • Human
  • Derivation
  • Phage display library
  • Type
  • Human IgG
  • Specificity
  • HIV-1 gp120
  • Species Reactivity
  • HIV
  • Clone
  • L17
  • Applications
  • ELISA, Neut
  • Related Disease
  • HIV infection

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp120 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Neutralization.

Target

  • Alternative Names
  • Human immunodeficiency virus Envelope glycoprotein GP120; HIV gp120

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone L17"

See other products for "HIV-1 gp120"

Recombinant Antibody

Single-domain Antibody

Chimeric Antibody

CAT Product Name Application Type
MRO-135LC Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) ELISA, WB, Neut Chimeric antibody (mouse/human)
MRO-135LC-S(P) Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)
MRO-135LC-F(E) Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4220 Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) WB, ELISA Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
PABX-101-S(P) Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment WB, ELISA, FuncS Human scFv

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for FAMAB-0056WJ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare