Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone V902) (CAT#: MRO-3618CQ)

Recombinant mouse antibody to gp120. V902 alone or in combination with other Abs was not able to trigger complement-mediated lysis (CML) of 93BR020 and 92UG037 HIV strains.


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ELISA

Figure 1 VCA with HIV and C‐HIV. ELISA plates were coated with mAb against C3 fragments (anti‐C3c/C3d Ab) or against gp120 and incubated with the non‐opsonized (HIV) or complement‐opsonized (C‐HIV) primary isolate 92BR030.

Figure 1 VCA with HIV and C‐HIV. ELISA plates were coated with mAb against C3 fragments (anti‐C3c/C3d Ab) or against gp120 and incubated with the non‐opsonized (HIV) or complement‐opsonized (C‐HIV) primary isolate 92BR030.

The presence of C3 fragments or the accessibility of gp120 is reflected by an increase in the p24 signal. As expected, HIV is recognized by several anti‐gp120 Ab (TH8, 178.1, CRA3, V902), but does not bind to the anti‐C3c/C3d Ab.

Pruenster, M., Wilflingseder, D., Banki, Z., Ammann, C. G., Muellauer, B., Meyer, M., ... & Stoiber, H. (2005). C-type lectin-independent interaction of complement opsonized HIV with monocyte-derived dendritic cells. European Journal of Immunology, 35(9), 2691-2698.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Recognizes HIV-1 gp120
  • Species Reactivity
  • HIV-1
  • Clone
  • V902
  • Applications
  • ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Recombinant Antibody

Single-domain Antibody

Chimeric Antibody

CAT Product Name Application Type
MRO-135LC Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) ELISA, WB, Neut Chimeric antibody (mouse/human)
MRO-135LC-S(P) Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)
MRO-135LC-F(E) Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4220 Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) WB, ELISA Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
PABX-101-S(P) Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment WB, ELISA, FuncS Human scFv

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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