Human Anti-HIV-1 gp160 Recombinant Antibody (clone 64B9/A6) (CAT#: MRO-3752CQ)

Recombinant human antibody to gp160(139-155). This antibody is V1-specific MAb and could potently neutralize autologous strain SF162.


Specific Inquiry
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  • Published Data
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Neut

Figure 1 Representative neutralization assays of Xeno-mAbs.

Figure 1 Representative neutralization assays of Xeno-mAbs.

HIVNL4–3-luc virus was pseudotyped with HIVSF162 envelope proteins, comparing V1 and V2-specific mAbs.

He, Y., Honnen, W. J., Krachmarov, C. P., Burkhart, M., Kayman, S. C., Corvalan, J., & Pinter, A. (2002). Efficient isolation of novel human monoclonal antibodies with neutralizing activity against HIV-1 from transgenic mice expressing human Ig loci. The Journal of Immunology, 169(1), 595-605.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG2, κ
  • Specificity
  • Recognizes HIV-1 gp160(139-155)
  • Species Reactivity
  • HIV-1
  • Clone
  • 64B9/A6
  • Applications
  • Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp160 antibody has been reported in applications of Neutralization.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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