Recombinant human antibody to gp41. m46 binds to a conformational epitope on gp41 and did not compete with 2F5, 4E10 or Z13. It can bind to a 5 helix bundle, but not to N-heptad repeat coil-coils or a 6-helix bundle. It is broadly neutralizing.
Figure 1 Immunoprecipitation screen of the M series monoclonal antibodies.
Ad5-infected HeLa cells were labeled with methionine 14 to 18 h postinfection.
Harlow, E., Franza, B. R., & Schley, C. A. R. O. L. (1985). Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products. Journal of virology, 55(3), 533-546.
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• Confirmed specificity
• High repeatability
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-486-S(P) | Recombinant Anti-HIV-1 gp41 Antibody scFv Fragment | FC, WB, FuncS | scFv |
MRO-4195CQ-S(P) | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 9303); scFv Fragment | WB, FC | Mouse scFv |
HPAB-0735-WJ-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (HPAB-0735-WJ-S(P)) | Neut | Human scFv |
PABJ-0150-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone N6 FR3-03); scFv Fragment | ELISA, Neut | Human scFv |
PABJ-0179-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PABJ-0179-S(P)) | ELISA, Neut, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-486 | Recombinant Human Anti-HIV-1 gp41 Antibody | ELISA, IP, FuncS | IgG |
PABL-185 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8062) | WB, ELISA, FuncS | Human IgG |
PABL-186 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5) | WB, Neut, FuncS | Human IgG |
PABL-187 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC176) | Neut, FuncS | Human IgG |
PABL-188 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC315) | Neut, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-486-F(E) | Recombinant Human Anti-HIV-1 gp41 Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
MRO-4138CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10E8-10fH/4fL); Fab Fragment | Neut | Human Fab |
MRO-4139CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10E8-19fH/10fL); Fab Fragment | Neut | Human Fab |
MRO-4140CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10E8-2fH/10fL); Fab Fragment | Neut | Human Fab |
MRO-4141CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10E8-2fH/4fL); Fab Fragment | Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-025LC | Anti-HIV-1 gp41 Recombinant Antibody (4E10-IgG3) | ELISA | Human antibody |
MRO-026LC | Anti-HIV-1 gp41 Recombinant Antibody (4E10-IgG1) | ELISA | Human antibody |
MRO-040LC | Anti-HIV-1 gp41 Recombinant Antibody (M66.6) | ELISA | Human antibody |
MRO-074LC | Anti-HIV-1 gp41 Recombinant Antibody (W) | ELISA | Human antibody |
MRO-077LC | Anti-HIV-1 gp41 Recombinant Antibody (3D6) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC746 | A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer | FCM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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