Camelid Anti-NadA Recombinant Antibody (HPAB-A1201-YJ) (CAT#: HPAB-A1201-YJ)

This product is a Camelid antibody that recognizes NadA.


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Figure 1 VHH Interacting with NadA peptides could block the interaction between rec-NadA and proteins of hBMEC.

Figure 1 VHH Interacting with NadA peptides could block the interaction between rec-NadA and proteins of hBMEC.

Preincubated was performed to block receptor binding site on rec-NadA by VHH selected against either NadA-gdA33−K69 (C) or NadA-ccL121−K158 (D) or combination of VHH selected against NadA-gdA33−K69 and NadA-ccL121−K158 (E).

Kulkarni, A., Mochnáčová, E., Majerova, P., Čurlík, J., Bhide, K., Mertinková, P., & Bhide, M. (2020). Single domain antibodies targeting receptor binding pockets of Nada restrain adhesion of neisseria meningitidis to human brain microvascular endothelial cells. Frontiers in Molecular Biosciences, 7, 573281.


Specifications

  • Host Species
  • Camelid
  • Derivation
  • Llama
  • Type
  • Camelid VHH
  • Specificity
  • N. meningitides NadA
  • Species Reactivity
  • N. meningitides
  • Clone
  • HPAB-A1201-YJ
  • Applications
  • ELISA

Product Property

  • Purification
  • Affinity Purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • See the COA
  • Buffer
  • PBS
  • Storage
  • Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • Neisseria adhesin A; Neisseria; adhesin A; N. meningitides; Neisseria meningitides

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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