Rabbit Anti-NR0B1 Recombinant Antibody (clone R02-7W2) (CAT#: VS3-XY3452)
The rabbit recombinant antibody specifically recognizes NR0B1 (Nuclear receptor subfamily 0 group B member 1), which may have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency. It specifically reacts with human NR0B1. It has been tested using Western Blot, Immunohistochemistry-Paraffin, Flow cytometry, Immunocytochemistry or Immunofluorescence.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61948/1470_A6_4_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61948/1470_A6_4_selected.jpg
Figure 2 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to nuclear speckles & centriolar satellites.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67207/1423_E2_2_selected.jpg
(Immunofluorescent staining of human cell line RT4 shows localization to nuclear speckles & centriolar satellites.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67207/1423_E2_2_selected.jpg
Figure 3 RNA cell line category: Group enriched (A549, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169297-NR0B1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169297-NR0B1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human NR0B1
- Species Reactivity
- Human
- Clone
- R02-7W2
- Applications
- WB, IHC-P, ICC, IF, FC
- Related Disease
- Adrenal Hypoplasia, Congenital; 46,Xy Sex Reversal 2
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
FC: 1/50-1/100
Target
- Alternative Names
- AHC; AHX; DSS; GTD; HHG; AHCH; DAX1; DAX-1; NROB1; SRXY2
- Gene ID
- 190
- UniProt ID
- P51843
- Long Name
- Nuclear receptor subfamily 0 group B member 1
- Cellular Localization
- Nucleus, Cytoplasm
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P51843)
Modification sites at neXtProt (NX_P51843)
Glycosylation from GlyGen (P51843) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_000466.2
- Function
- Orphan nuclear receptor.
Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis.
Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions.
May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NR0B1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1446CT | Recombinant Mouse anti-Human NR0B1 Monoclonal antibody (1F10) | ELISA, WB | |
| MRO-1110-CN | Recombinant Rabbit Anti-NR0B1 Monoclonal Antibody (JU33-05) | WB, IF, FC | Rabbit IgG |
| VS3-WK650 | Rabbit Anti-NR0B1 Recombinant Antibody (clone JU33-05) | WB, ELISA | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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