Human Anti-P. falciparum MSP3 Recombinant Antibody (clone RAM3) (CAT#: FAMAB-0275JF)

Recombinant monoclonal antibody specially binds to Plasmodium falciparum MSP-3 and MSP-6. RAM3 is a human monoclonal antibody that can be widely used in the study of Plasmodium falciparum malaria.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
IHC

Figure 1 Microscopy of anti-plasmodial action of ΔFd on Plasmodium falciparum.

Figure 1 Microscopy of anti-plasmodial action of ΔFd on Plasmodium falciparum.

Note the selectivity in action on parasitized cells with no effect on uninfected cells.

Kaushik, N. K., Sharma, J., & Sahal, D. (2012). Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides. Malaria journal, 11(1), 1-16.

ELISA

Figure 2 MSP3-heme complex possesses peroxidase activity.

Figure 2 MSP3-heme complex possesses peroxidase activity.

These nascent heme molecules are entrapped by soluble MSP3 fibrils which modulates its peroxidase activity that might have antioxidant properties of some biological relevance.

Imam, M., Singh, S., & Kumar, N. (2013). Plasmodium falciparum Merozoite Surface.


Specifications

  • Host Species
  • Human
  • Derivation
  • Human phage display Fab library
  • Type
  • Human IgG
  • Specificity
  • Plasmodium falciparum MSP-3, MSP-6
  • Species Reactivity
  • P. falciparum
  • Clone
  • RAM3
  • Applications
  • ELISA, IHC
  • Related Disease
  • Plasmodium falciparum malaria

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The P. falciparum MSP3 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Immunohistochemistry.

Target

  • Alternative Names
  • MSP-3; Merozoite surface antigen 3

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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