This chicken anti-T. stejnegeri venom proteins antibody (clone TSL2) is a product that recognizes T. stejnegeri venom proteins.
Figure 1 Binding analysis of anti-TS scFvs to various venom proteins.
Venom proteins collected from snakes DA, BM, TS, TM, NNA, and DRF were coated on ELISA wells and incubated with the individual, purified scFvs (5 μg/mL).
Figure 2 Binding analysis of anti-TS scFvs using competitive ELISA.
Only 6.25 μg/mL of free TS proteins were needed to achieve more than 50% suppression on binding activities of TSL1 (57%) and TSL7 (57%). 12.5, 12.5, 25, and 100 μg/mL of TS proteins were needed to achieve the same inhibitory effects on binding activities of TSS1 (69%), TSS13 (68%), TSL2 (82%) and TSL8 (67%).
Figure 3 Calculated dissociation constant (Kd) values of anti-TS antibodies.
Figure 4 Neutralization analysis of anti-TS scFvs in mice.
Polyclonal IgY antibodies from pre-immunized (Pre-IgY) or immunized (Imm-IgY) hens, equine-derived antivenom (4 mg), or a combination of six anti-TS scFvs (1 and 4 mg) were individually incubated with TS venom proteins at 37 °C for 1 h. These preparations were injected into mice, which were recorded hourly for 36 h.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0323-CJ54 | Chicken Anti-T. stejnegeri venom proteins Recombinant Antibody (clone TSS1) | ELISA, WB, Neut, Inhib, IA | Chicken IgY |
VS-0323-CJ55 | Chicken Anti-T. stejnegeri venom proteins Recombinant Antibody (clone TSS13) | ELISA, WB, Neut, Inhib, IA | Chicken IgY |
VS-0323-CJ56 | Chicken Anti-T. stejnegeri venom proteins Recombinant Antibody (clone TSL1) | ELISA, WB, Neut, Inhib, IA | Chicken IgY |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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