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CLCN4
CLCN4 (Chloride Voltage-Gated Channel 4) is a Protein Coding gene. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Diseases associated with CLCN4 include Raynaud-Claes Syndrome and Non-Syndromic X-Linked Intellectual Disability.
Protein class
Disease related genes, Human disease related genes, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Cone photoreceptor cells, Bipolar cells, Oligodendrocytes, Inhibitory neurons, Horizontal cells, Excitatory neurons, Rod photoreceptor cells)
Immune cell specificity
Immune cell enhanced (naive B-cell, neutrophil)
Cell line specificity
Cell line enhanced (GAMG, HEL, SCLC-21H)
Interaction
Monomer (PubMed:28972156). Forms heterodimers with CLCN3 (PubMed:28972156).
More Types Infomation
- Recombinant Human Anti-CLCN4 Soluble TCR (IB1) (KIH) (VS-0622-YF6576)
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- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (FE3) (KIH) (VS-0622-YF6575)
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- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (LH6) (C-Cys) (VS-0622-YF3871)
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (LE6) (C-Cys) (VS-0622-YF3870)
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- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (KH12) (C-Cys) (VS-0622-YF3869)
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (IB1) (C-Cys) (VS-0622-YF3868)
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (FE3) (C-Cys) (VS-0622-YF3867)
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (LH6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1163)
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (LE6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1162)
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (KH12) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1161)
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (IB1) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1160)
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Recombinant Human Anti-CLCN4 Soluble TCR (FE3) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1159)
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Rabbit Anti-CLCN4 Recombinant Antibody (clone rN222/6) (VS-0422-LC51)
-
- Species Reactivity: Rat, Human, Mouse
- Type: Rabbit IgG
- Application: ICC, WB, IHC
- Human Anti-CLCN4 Recombinant Antibody (clone hN222/6) (VS-0422-LC50)
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- Species Reactivity: Rat, Human, Mouse
- Type: Human IgG1
- Application: ICC, WB, IHC
- Rat Anti-CLCN4 Recombinant Antibody (clone rtN222/6) (VS-0422-LC49)
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- Species Reactivity: Rat, Human, Mouse
- Type: Rat IgG2b
- Application: ICC, WB, IHC
- Mouse Anti-CLCN4 Recombinant Antibody (clone mN222/6) (VS-0422-LC48)
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- Species Reactivity: Rat, Human, Mouse
- Type: Mouse IgG1
- Application: ICC, WB, IHC
- Human Anti-CLCN4 Recombinant Soluble TCR (LH6) (scTCR-410ZP-S(P))
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Human Anti-CLCN4 Recombinant Soluble TCR (LE6) (scTCR-409ZP-S(P))
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Human Anti-CLCN4 Recombinant Soluble TCR (KH12) (scTCR-408ZP-S(P))
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
- Human Anti-CLCN4 Recombinant Soluble TCR (IB1) (scTCR-407ZP-S(P))
-
- Species Reactivity: Human
- Epitope: LLAGTLAGV
- MHC: HLA-DRB5
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For Research Use Only. Not For Clinical Use.