Disease related genes, Human disease related genes, Plasma proteins, Transcription factors
Intracellular
Cell type enhanced (Oligodendrocytes)
Immune cell enhanced (basophil)
Low cell line specificity
Interacts with MBD2 and MBD3 (PubMed:11756549, PubMed:12183469, PubMed:16415179). Interaction with MBD2 is required for the enhancement of MBD2-mediated repression and for targeting to the chromatin (PubMed:11756549, PubMed:12183469, PubMed:16415179). Component of the MeCP1 histone deacetylase complex (PubMed:11756549). Interacts with histone tails, including that of histones H2A, H2B, H3 and H4 (PubMed:16415179). Interacts with ERCC6 (PubMed:26030138).
Repressor
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For Research Use Only. Not For Clinical Use.