Histones and DNA associate to form nucleosomes, the basic repeating units of chromatin. Nucleosome subparticles (or subnucleosomes) composed of dimers of H2A/H2B, tetramers of H32/H42 and single molecules of H1, all associated with DNA of various lengths, can be released by micrococcal nuclease digestion and urea treatment.
Histones and DNA associate to form nucleosomes, the basic repeating units of chromatin. Nucleosome subparticles (or subnucleosomes) composed of dimers of H2A/H2B, tetramers of H32/H42 and single molecules of H1, all associated with DNA of various lengths, can be released by micrococcal nuclease digestion and urea treatment.