Intracellular
Cell type enhanced (Microglial cells, Oligodendrocytes, Inhibitory neurons)
Immune cell enhanced (basophil)
Cell line enhanced (HUVEC TERT2, SCLC-21H, SH-SY5Y, WM-115)
Interacts through its N-terminal region with the ankyrin repeat region of the Notch proteins NOTCH1, NOTCH2, NOTCH3 and NOTCH4. Forms a DNA-binding complex with Notch proteins and RBPSUH/RBP-J kappa.
Activator
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For Research Use Only. Not For Clinical Use.