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OGN
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants.
Protein class
Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Group enriched (Fibroblasts, Peritubular cells, Leydig cells, Endometrial stromal cells)
Immune cell specificity
Immune cell enriched (T-reg)
Cell line specificity
Group enriched (ASC TERT1, HSkMC, JURKAT, MOLT-4)
Molecular function
Growth factor
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.