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PKP3

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways.
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Distal enterocytes, Paneth cells, Proximal enterocytes, Extravillous trophoblasts, Undifferentiated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (A-431, CAPAN-2, HaCaT, hTCEpi, MCF7, SK-BR-3)

More Types Infomation

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