Disease related genes, Human disease related genes
Intracellular
Cell type enhanced (Late spermatids)
Immune cell enhanced (neutrophil)
Low cell line specificity
Interacts with ATG16L1 (PubMed:21808068). Interaction with ATG16L1 is important for autophagosome formation (By similarity). Interacts with ATG16L2; however interaction is approximately hundred times lower than for ATG16L1 (By similarity). Interacts with RIC1 (via C-terminus domain); the interaction is direct with a preference for RAB33B-GTP (PubMed:23091056). Interacts with RGP1 (PubMed:23091056).
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For Research Use Only. Not For Clinical Use.