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RCVRN
This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.
Protein class
Plasma proteins, Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Rod photoreceptor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (WM-115)
Interaction
Homodimer; disulfide-linked (By similarity). Homodimerization is caused by prolonged intense illumination (By similarity). May form a complex composed of RHO, GRK1 and RCVRN in a Ca(2+)-dependent manner; RCVRN prevents the interaction between GRK1 and RHO (By similarity). Interacts (via C-terminus) with GRK1 (via N-terminus); the interaction is Ca(2+)-dependent (By similarity).
More Types Infomation
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- Species Reactivity: Human
- Application: ELISA, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, ICC, IF, IHC
- Rabbit Anti-RCVRN Recombinant Antibody (clone AFY0042) (MOR-0071-FY)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IF, IHC-P, WB
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For Research Use Only. Not For Clinical Use.