Intracellular
Cell type enhanced (Oligodendrocyte precursor cells, Inhibitory neurons, Excitatory neurons, Enteroendocrine cells)
Not detected in immune cells
Cell line enhanced (ASC TERT1, hTERT-HME1, LHCN-M2, RH-30, U-87 MG)
Interacts with GNAI1 and GNAQ (PubMed:18434541). Interacts with GNAZ and GNAI2. Interacts with OPRM1. Forms a complex with mu-opioid receptors and G(alpha)z/i2 subunits, including GNAZ and GNAI2; the formation of this complex results in mu-opioid receptor desensitization (By similarity). Interacts with HINT1 (By similarity).
GTPase activation, Signal transduction inhibitor
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For Research Use Only. Not For Clinical Use.