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RGS8
This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Bipolar cells, Late spermatids, Inhibitory neurons, Theca cells, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, Daudi, SCLC-21H, U-698)
Interaction
Interacts with GNAO1 (By similarity). Interacts with GNAI3.
Molecular function
GTPase activation, Signal transduction inhibitor
More Types Infomation
- Chicken Anti-RGS8 Polyclonal IgY (BRD-0508MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.