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SNX27

Protein class

Plasma proteins, Transporters

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Group enriched (neutrophil, classical monocyte, non-classical monocyte, intermediate monocyte, basophil, myeloid DC)

Cell line specificity

Low cell line specificity

Interaction

Core component of the SNX27-retromer, a multiprotein complex composed of SNX27, the WASH complex and the retromer complex. Interacts (via PDZ domain) with a number of target transmembrane proteins (via PDZ-binding motif): ABCC4, ADRB2, ARHGEF7, GRIA1, GRIA2, GRIN1, GRIN2A GRIN2C, KCNJ6, KCNJ9 and SLC2A1/GLUT1. Interacts (via the FERM-like regions) with the WASH complex. Interacts with SNX1. Interacts with CYTIP. Isoform 1 and isoform 2 directly interact with DGKZ. Isoform 1 and isoform 2 interact with HT4R isoform 5-HTA(A). Interacts with MCC.

More Types Infomation

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