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SYT2
This gene encodes a synaptic vesicle membrane protein. The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis. Mutations in this gene are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. Alternative splicing results in multiple transcript variants.
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Excitatory neurons, Inhibitory neurons, Oligodendrocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AF22, NTERA-2)
Interaction
Homotetramer (Probable). Interacts with STON2 (PubMed:11381094). Interacts with SCAMP5 (PubMed:19234194). Interacts with PRRT2 (By similarity).
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB
- Mouse Anti-SYT2 Recombinant Antibody (clone 6H5) (MOB-2444z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IP
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- Species Reactivity: Human
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.