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TSTA3
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Syncytiotrophoblasts, Cytotrophoblasts, Hofbauer cells, Adipocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer.
Molecular function
Isomerase, Multifunctional enzyme, Oxidoreductase
More Types Infomation
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- Species Reactivity: Human
- Application: WB
- Chicken Anti-TSTA3 Polyclonal IgY (BRD-0605MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.