Disease related genes, Human disease related genes
Intracellular
Group enriched (Muller glia cells, Horizontal cells, Distal tubular cells, Skeletal myocytes)
Not detected in immune cells
Cell line enhanced (AF22, CACO-2, NTERA-2, RPMI-8226, SCLC-21H, SH-SY5Y, SuSa)
Dimer of alpha and beta chains (PubMed:23001566, PubMed:28013290, PubMed:26732629). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
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For Research Use Only. Not For Clinical Use.