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TYMP

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.
Protein class

Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (monocytes, Exocrine glandular cells, Macrophages, Hofbauer cells)

Immune cell specificity

Group enriched (classical monocyte, neutrophil, intermediate monocyte, non-classical monocyte, eosinophil, myeloid DC)

Cell line specificity

Cell line enhanced (CAPAN-2, HHSteC, Karpas-707, U-266/70)

Interaction

Homodimer.

Molecular function

Developmental protein, Glycosyltransferase, Growth factor, Transferase

More Types Infomation

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