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UGT2B15

This gene encodes a member of the UDP-glycosyltransferase (UDPGT) family. The UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein displays activity towards several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.
Protein class

Enzymes, Metabolic proteins

Predicted location

Membrane

Single cell type specificity

Group enriched (Cholangiocytes, Hepatocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Molecular function

Glycosyltransferase, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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