This immunotoxin was achieved by conjugating/fusing the HRGβ2 to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to cells overexpressing erbB3 and enters cells by receptor-mediated endocytosis, then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treatment of prostate, gastric and pancreatic cancers.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1729-sdAb | Recombinant Anti-human ERBB3 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
TAB-070CT | Llama Anti-ERBB3 Recombinant Single Domain Antibody (TAB-070CT) | FC, Block | Llama VHH |
PABC-556 | Recombinant Llama Anti-ERBB3 Single Domain Antibody (BCD090-M2) | ELISA, SPR | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-189 | Human Anti-ERBB3 Recombinant Antibody (TAB-189) | IP, IF, FuncS, FC, Neut, ELISA, ICC | Human IgG1, κ |
TAB-065CT | Human Anti-ERBB3 Recombinant Antibody (TAB-065CT) | ELISA, FC | Human IgG1 |
TAB-062CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-062CT-S(P)) | ELISA, Inhib, FC | Human scFv |
TAB-065CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-065CT-S(P)) | ELISA, FC | Human scFv |
TAB-066CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-066CT-S(P)) | ELISA, Inhibion, FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H47 | Anti-Human ERBB3 Recombinant Antibody (Lumretuzumab) | ELISA, Inhib | Human IgG1, κ |
HPAB-0181-FY | Human Anti-ERBB3 Recombinant Antibody (HPAB-0181-FY) | ELISA, FC | Human IgG1 |
HPAB-0182-FY | Human Anti-ERBB3 Recombinant Antibody (HPAB-0182-FY) | ELISA, FC | Human IgG |
HPAB-0183-FY | Human Anti-ERBB3 Recombinant Antibody (HPAB-0183-FY) | ELISA, FC | Human IgG |
HPAB-0184-FY | Human Anti-ERBB3 Recombinant Antibody (HPAB-0184-FY) | ELISA, FC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H22 | Anti-Human ERBB3 Recombinant Antibody (Duligotuzumab) (TAB-H22) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 - kappa |
TAB-057CT | Human Anti-ERBB3 Recombinant Antibody (TAB-057CT) | Inhibion, ELISA | Humanized antibody |
TAB-058CT | Human Anti-ERBB3 Recombinant Antibody (TAB-058CT) | ELISA, Inhib, Cty, IHC, WB, FC | Human IgG1, κ |
TAB-057CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-057CT-F(E)) | Inhibion, ELISA | Humanized Fab |
TAB-063CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-063CT-F(E)) | ELISA, Inhib, FC | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-086 | Human Anti-ERBB3 Recombinant Antibody (clone KTN3379); Fab Fragment | ELISA, WB, IF, FuncS | Human Fab |
HPAB-M0305-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 11G01); Fab Fragment | ELISA, Neut | Mouse Fab |
HPAB-M0306-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 12A07); Fab Fragment | ELISA, Neut | Mouse Fab |
HPAB-M0307-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 18H02); Fab Fragment | ELISA, Neut | Mouse Fab |
HPAB-M0309-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 24C05); Fab Fragment | ELISA, Neut | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0508CL-S(P) | Anti-Human ERBB3 Recombinant Antibody scFv Fragment (1A5) | ELISA, Inhib, FuncS | |
TAB-0509CL-S(P) | Anti-Human ERBB3 Recombinant Antibody scFv Fragment (3D4) | ELISA, Inhib, FuncS | |
TAB-0508CL-F(E) | Anti-Human ERBB3 Recombinant Antibody Fab Fragment (1A5) | ELISA, Inhib, FuncS | |
TAB-0509CL-F(E) | Anti-Human ERBB3 Recombinant Antibody Fab Fragment (3D4) | ELISA, Inhib, FuncS | |
TAB-060CT | Rabbit Anti-ERBB3 Recombinant Antibody (TAB-060CT) | Inhib, ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-061CT | Human Anti-ERBB3 Recombinant Antibody (TAB-061CT) | Inhib, ELISA | Chimeric (Rabbit/Human) antibody |
TAB-061CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-061CT-S(P)) | Inhib, ELISA | Human scFv |
TAB-061CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-061CT-F(E)) | Inhib, ELISA | Chimeric (Rabbit/Human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-738CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL932) | Neut, IP | Mouse IgG1 |
NEUT-739CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL483) | FC, CyTOF®, ELISA, Neut | Mouse IgG1 |
NEUT-740CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1019) | Neut | Human IgG1, κ |
NEUT-741CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1020) | Neut | Human IgG1, κ |
NEUT-742CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone M908) | Neut | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1179 | Hi-Affi™ Rabbit Anti-ERBB3 Recombinant Antibody (clone DS1179AB) | ICC, IF, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H21 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-422CQ | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Elgemtumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
AFC-TAB-189 | Afuco™ Anti-ERBB3 Recombinant Antibody (AFC-TAB-189), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | Human IgG1, κ |
AFC-TAB-H22 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotuzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-892 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Seribantumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0608-WJ-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (HPAB-0608-WJ-S(P)) | ELISA, IHC | Humanized scFv |
HPAB-0609-WJ-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (HPAB-0609-WJ-S(P)) | ELISA, IHC | Humanized scFv |
HPAB-0610-WJ-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (HPAB-0610-WJ-S(P)) | ELISA, IHC | Humanized scFv |
HPAB-0611-WJ-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (HPAB-0611-WJ-S(P)) | ELISA, IHC | Humanized scFv |
PSBS-0069 | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (PSBS-0069) | ELISA, Block, FuncS | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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