This product is a recombinant human antibody that recognizes EPCAM. This product is a human monoclonal antibody that is capable of binding to human Ep-CAM.
Figure 1 Localization of the fully human anti-EpCAM-directed UBS54 Ab applied i.p. in EpCAM-transgenic FVB/N-C57BL/6 hybrid mice.
UBS54 localization was determined immunohistochemically 48 h after injection by staining with an anti-human IgG peroxidase conjugate. UBS54 localized on the EpCAM-expressing epithelial cell lining of the kidney (a), uterus (c), bladder (e), pancreas (f), colon (h), lung (j), liver (k), and salivary glands (o), whereas no UBS54 was observed in EpCAM-negative tissues, such as, for instance, heart (m). No specific staining was observed after incubation of similar EpCAM-expressing tissue sections obtained from transgenic mice injected with PBS: kidney (b), uterus (d), pancreas (g), colon (i), liver (l), and on slides of EpCAM-negative heart tissue (n).
Kosterink, J. G., McLaughlin, P. M., Lub-de Hooge, M. N., Hendrikse, H. H., van Zanten, J., van Garderen, E.,... & de Leij, L. F. (2007). Biodistribution studies of epithelial cell adhesion molecule (EpCAM)-directed monoclonal antibodies in the EpCAM-transgenic mouse tumor model. The Journal of Immunology, 179(2), 1362-1368.
Figure 2 Biodistribution of ̶¹²⁵I-labeled mAbs in most relevant tissues and organs in EpCAM-transgenic FVB/N-V57BL/6 hybrid mice and in nontransgenic FVB/N-C57BL/6 hybrid mice 48 h after injection.
Biodistribution is expressed as tissue-to-blood ratio per gram tissue.
Kosterink, J. G., McLaughlin, P. M., Lub-de Hooge, M. N., Hendrikse, H. H., van Zanten, J., van Garderen, E.,... & de Leij, L. F. (2007). Biodistribution studies of epithelial cell adhesion molecule (EpCAM)-directed monoclonal antibodies in the EpCAM-transgenic mouse tumor model. The Journal of Immunology, 179(2), 1362-1368.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-213 | Humanized Anti-EPCAM Recombinant Antibody (clone Tucotuzumab) | WB, Neut, ELISA, IF, IP, FuncS, FC | Humanized (from mouse) IgG1 |
TAB-362MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (3622W94) | Confocal, ELISA | Humanized antibody |
TAB-374MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (h12H8B) | FC, ELISA | Humanized antibody |
TAB-375MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (h12H8C) | FC, ELISA | Humanized antibody |
TAB-376MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (h2D11B) | FC, ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L013E | anti-EPCAM immunotoxin MOC31 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L013D | anti-EPCAM immunotoxin MOC31 (IgG)-DT | Cytotoxicity assay, Functional assay | |
AGTO-L013G | anti-EPCAM immunotoxin MOC31 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
AGTO-L013R | anti-EPCAM immunotoxin MOC31 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L013O | anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-356MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (3-171) | FC, ELISA | Human antibody |
TAB-357MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (7-F17) | FC, ELISA | Human antibody |
TAB-358MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (12-C15) | FC, ELISA | Human antibody |
TAB-359MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (16-G5) | FC, ELISA | Human antibody |
TAB-360MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (17-C20) | FC, ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-363MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-363MZ-S(P)) | Confocal, ELISA | Mouse scFv |
TAB-364MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-364MZ-S(P)) | NIR (Near-infrared) fluorescence imaging, ELISA | Mouse scFv |
TAB-365MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-365MZ-S(P)) | NIR (Near-infrared) fluorescence imaging, ELISA | Mouse scFv |
TAB-366MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-366MZ-S(P)) | ELISA, WB, IHC | Mouse scFv |
TAB-367MZ-S(P) | Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-367MZ-S(P)) | ELISA, WB, IHC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1163 | Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB) | IHC-P, WB, ICC, ICC, IF | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-0537-CN | Rabbit Anti-EPCAM Recombinant Antibody (clone CBACN-213) | WB, IHC | Rabbit IgG |
MRO-0538-CN | Mouse Anti-EPCAM Recombinant Antibody (clone 3-E1-E2) | WB, IF, IHC, FC | Mouse IgM |
MRO-1842-CN | Rabbit Anti-EPCAM Polyclonal Antibody (MRO-1842-CN) | WB, IF, IHC | Rabbit IgG |
HPAB-2216LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2216LY) | ELISA | Human IgG |
HPAB-2217LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2217LY) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-106 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Adecatumumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
AFC-TAB-213 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Tucotuzumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
AFC-TAB-701 | Afuco™ Anti-EpCAM ADCC Recombinant Antibody (Edrecolomab), ADCC Enhanced | ELISA, IP, FC, FuncS, IF, Neut | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2216LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2216LY-F(E)) | ELISA | Human Fab |
HPAB-2217LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2217LY-F(E)) | ELISA | Human Fab |
HPAB-2218LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2218LY-F(E)) | ELISA | Human Fab |
HPAB-2219LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2219LY-F(E)) | ELISA | Human Fab |
HPAB-2220LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2220LY-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0031 | APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM | |
MHC-CN0032 | PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1520-FY-F(E) | Mouse Anti-EPCAM Recombinant Antibody (clone 2A9); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-1521-FY-F(E) | Mouse Anti-EPCAM Recombinant Antibody (clone FMU-EPCAM-4E4); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-1522-FY-F(E) | Mouse Anti-EPCAM Recombinant Antibody (clone FMU-EPCAM-4F6); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-2050-FY-S(P) | Human Anti-EpCAM Recombinant Antibody (clone K53); scFv Fragment | FC | Human scFv |
HPAB-2051-FY-S(P) | Human Anti-EpCAM Recombinant Antibody (clone 02-237); scFv Fragment | FC | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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