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    Anti-Human EPCAM Recombinant Antibody Fab Fragment (h12H8C) (CAT#: TAB-375MZ-F(E))

    This antibody specifically binds to epithelial cell adhesion/activating molecule EpCAM expressed on cancer cells, which can induce cancer cell apoptosis. The antibody can be potentially used as diagnostic and therapeutic agents.

    Specific Inquiry
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    • Conjugation:

    • Endotoxin:

    • Purity:

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line MCF7
    Figure 1 IF staining of human cell line MCF7
    (Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67463/1592_H11_2_selected.jpg
    Normal Tissue
    Figure 2 Thyroid gland
    Figure 2 Thyroid gland
    (Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_B_2_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endocrine cells
    Staining: High
    Intensity: Strong
    Enterocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Enterocytes - Microvilli
    Staining: High
    Intensity: Strong
    Goblet cells
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_9_3.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Collecting ducts
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_8_5.jpg
    RNA Expression
    Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
    Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119888-EPCAM
    Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
    Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119888-EPCAM

    Specifications

    • Host Species
    • Human
    • Type
    • Humanized antibody
    • Specificity
    • Human
    • Clone
    • h12H8C
    • Applications
    • Flow Cytometry, Enzyme-linked Immunosorbent Assay
    • Related Disease
    • Cancers such as breast cancer, colorectal cancer, gastric cancer, lung cancer, and prostate cancer

    Target

    • Alternative Names
    • EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    See other products for "EPCAM"

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    CAT Product Name Application Type
    TAB-701 Anti-Human EpCAM/17-1A Recombinant Antibody (Edrecolomab) ELISA, IP, FC, FuncS, IF, Neut IgG2a - kappa
    TAB-0531CL Anti-Human EPCAM Recombinant Antibody (HE2) ELISA, Inhib
    TAB-363MZ-F(E) Mouse Anti-EPCAM Recombinant Antibody; Fab Fragment (TAB-363MZ-F(E)) Confocal, ELISA Mouse Fab
    TAB-364MZ-F(E) Mouse Anti-EPCAM Recombinant Antibody; Fab Fragment (TAB-364MZ-F(E)) NIR (Near-infrared) fluorescence imaging, ELISA Mouse Fab
    TAB-365MZ-F(E) Mouse Anti-EPCAM Recombinant Antibody; Fab Fragment (TAB-365MZ-F(E)) NIR (Near-infrared) fluorescence imaging, ELISA Mouse Fab

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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