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EPCAM
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Anti-EPCAM Recombinant Antibody Products
- Anti-EpCAM (B38.1)-Mal-dPEG4-NHS-DM1 ADC (ADC-111LCT)
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- Target: EpCAM
- Linker: PEG4Mal
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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- Anti-EpCAM (B38.1)-SMCC-DM1 ADC (ADC-112LCT)
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- Target: EpCAM
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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- Anti-EpCAM-SMCC-DM1 ADC (ADC-099LZY)
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- Target: EpCAM
- Linker: SMCC (N-succinimidyl-4-(N-maleimidomethyl)-cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Anti-EpCAM-SPDB-DM4 ADC (ADC-100LZY)
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- Target: EpCAM
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Anti-EpCAM-sulfo-SPDB-DM4 ADC (ADC-101LZY)
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- Target: EpCAM
- Linker: sulfo-SPDB(sulfo-N-succinimidyl 4-(2-pyridyldithio)butyrate
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Anti-EpCAM (clone MOC31)-hydrazone-Doxorubicin ADC (ADC-149LZY)
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- Target: EpCAM
- Linker: acid-cleavable hydrazone
linker - Drug: Doxorubicin
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For Research Use Only. Not For Clinical Use.
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.