EPCAM
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1
- Application: FC, IHC, FuncS, Inhib, Cyt
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA, FuncS
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- Anti-Human EPCAM Recombinant Antibody (3-171) (TAB-356MZ)
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: Cyt, ELISA, FC, WB
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- Anti-Human EPCAM Recombinant Antibody (7-F17) (TAB-357MZ)
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: ELISA
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- Anti-Human EPCAM Recombinant Antibody (12-C15) (TAB-358MZ)
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: ELISA
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- Anti-Human EPCAM Recombinant Antibody (16-G5) (TAB-359MZ)
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: ELISA
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- Anti-Human EPCAM Recombinant Antibody (17-C20) (TAB-360MZ)
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: ELISA
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- Anti-Human EPCAM Recombinant Antibody (24-G6) (TAB-361MZ)
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: ELISA
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- Anti-Human EPCAM Recombinant Antibody (h12H8B) (TAB-374MZ)
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- Type: Humanized antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody (h12H8C) (TAB-375MZ)
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- Type: Humanized antibody
- Application: FuncS, Inhib
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- Anti-Human EPCAM Recombinant Antibody (h2D11B) (TAB-376MZ)
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- Type: Humanized antibody
- Application: Cyt, Inhib
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (3-171) (TAB-356MZ-S(P))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (7-F17) (TAB-357MZ-S(P))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (12-C15) (TAB-358MZ-S(P))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (16-G5) (TAB-359MZ-S(P))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (17-C20) (TAB-360MZ-S(P))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (24-G6) (TAB-361MZ-S(P))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (3622W94) (TAB-362MZ-S(P))
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- Type: Humanized antibody
- Application: Confocal, ELISA
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Fab - G1 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (h12H8B) (TAB-374MZ-S(P))
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- Type: Humanized antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (h12H8C) (TAB-375MZ-S(P))
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- Type: Humanized antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (h2D11B) (TAB-376MZ-S(P))
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- Type: Humanized antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody Fab Fragment (3-171) (TAB-356MZ-F(E))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody Fab Fragment (7-F17) (TAB-357MZ-F(E))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody Fab Fragment (12-C15) (TAB-358MZ-F(E))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody Fab Fragment (16-G5) (TAB-359MZ-F(E))
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- Species Reactivity: Monkey
- Type: Human antibody
- Application: FC, ELISA
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- Mouse Anti-EPCAM Recombinant Antibody (clone MOC31) (FAMAB-0095YC)
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- Type: Mouse IgG1, κ
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, FC, IHC, IP, FuncS
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG1
- Application: WB, Neut, ELISA, IF, IP, FuncS, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG2a - kappa
- Application: ELISA, IP, FC, FuncS, IF, Neut
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- anti-EPCAM immunotoxin MOC31 (IgG)-PE (AGTO-L013E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-EPCAM immunotoxin MOC31 (IgG)-DT (AGTO-L013D)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-EPCAM immunotoxin MOC31 (IgG)-Gel (AGTO-L013G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-EPCAM immunotoxin MOC31 (IgG)-RTA (AGTO-L013R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin (AGTO-L013O)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Anti-Human EPCAM Recombinant Antibody (1G10) (TAB-368MZ)
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody (12H8) (TAB-369MZ)
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody (1F10) (TAB-370MZ)
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody (2D11) (TAB-371MZ)
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody (4D2 ) (TAB-372MZ)
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody (6D11) (TAB-373MZ)
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- Application: FC, ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: NIR (Near-infrared) fluorescence imaging, ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: NIR (Near-infrared) fluorescence imaging, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (1G10) (TAB-368MZ-S(P))
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (12H8) (TAB-369MZ-S(P))
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (1F10) (TAB-370MZ-S(P))
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (2D11) (TAB-371MZ-S(P))
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (4D2 ) (TAB-372MZ-S(P))
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- Application: FC, ELISA
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (6D11) (TAB-373MZ-S(P))
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- Application: FC, ELISA
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IgG4 (S to P)-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2 (D20T)
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; dI-IgG4-ala-IL2 (D20T)
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- Anti-Human EPCAM Recombinant Antibody Fab Fragment (HE2) (TAB-0531CL-F(E))
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- Application: ELISA, Inhib
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL12
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2 (D20T)
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; dI-IgG4 (FN>AQ)-ala-IL2 (D20T)
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Humanized from Mouse
- Cytokine 1 Species: Mouse
- Molecule Class: L Kappa; IgG2a-IL12
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2 (D20T)
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; De-glycosylated dI-IgG4-ala-IL2 (D20T)
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: scFv-IL12
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2 (N88R)
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG4-ala-IL2 (N88R)
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG4 (LSLS-ATAT)-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL12
- Cytokine 2: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Cytokine 2 Species: Human
- Molecule Class: IgG1-IL12-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2 (TTSR)
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG4-M1-IL2 (TTSR)
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG4 (N to Q)-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL12
- Cytokine 2: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Cytokine 2 Species: Human
- Molecule Class: IL12-IgG1-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: scIL12
- Host: Mouse
- Cytokine 1 Species: Mouse
- Molecule Class: IgG1-scIL12
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; PEGylated IgG4-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL12
- Cytokine 2: IL2
- Host: Mouse
- Cytokine 1 Species: Mouse
- Cytokine 2 Species: Mouse
- Molecule Class: IL12-IgG1-IL2
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- Anti-Human EPCAM Recombinant Antibody scFv Fragment (HE2) (TAB-0531CL-S(P))
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- Application: ELISA, Inhib
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: scIL12
- Host: Mouse
- Cytokine 1 Species: Mouse
- Molecule Class: scIL12-IgG1
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: GM-CSF
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: GM-CSF-FAB
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: scIL12
- Cytokine 2: IL2
- Host: Mouse
- Cytokine 1 Species: Mouse
- Cytokine 2 Species: Mouse
- Molecule Class: IgG1-scIL12-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: TNFα
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG4-(Deleted Lys)-TNFα
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: scIL12
- Cytokine 2: IL2
- Host: Mouse
- Cytokine 1 Species: Mouse
- Cytokine 2 Species: Mouse
- Molecule Class: scIL12-IgG1-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL4
- Cytokine 2: GM-CSF
- Host: Mouse
- Cytokine 1 Species: Human
- Cytokine 2 Species: Human
- Molecule Class: IgG1-IL4-GM-CSF
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL4
- Cytokine 2: GM-CSF
- Host: Mouse
- Cytokine 1 Species: Mouse
- Cytokine 2 Species: Mouse
- Molecule Class: IL4-IgG1-GM-CSF
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Cytokine 2: GM-CSF
- Host: Mouse
- Cytokine 1 Species: Mouse
- Cytokine 2 Species: Mouse
- Molecule Class: scFv-CH1-GM-CSF; scFv-Cκ-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Cytokine 2: GM-CSF
- Host: Human
- Cytokine 1 Species: Human
- Cytokine 2 Species: Human
- Molecule Class: scFv-CH1-GM-CSF; scFv-Cκ-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG4-ala-IL2 (D20T)
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL12-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IgG1-scIL12-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: scIL12-linker-IgG1-IL2
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- Target: EpCAM
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: scIL12-IgG1-IL2
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- Anti-Human EPCAM Recombinant Antibody (HE2) (TAB-0531CL)
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- Application: ELISA, Inhib
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- Anti-EpCAM (B38.1)-Mal-dPEG4-NHS-DM1 ADC (ADC-111LCT)
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- Target: EpCAM
- Linker: PEG4Mal
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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- Anti-EpCAM-SMCC-DM1 ADC (ADC-099LZY)
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- Target: EpCAM
- Linker: SMCC (N-succinimidyl-4-(N-maleimidomethyl)-cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Anti-EpCAM (B38.1)-SMCC-DM1 ADC (ADC-112LCT)
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- Target: EpCAM
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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- Anti-EpCAM-SPDB-DM4 ADC (ADC-100LZY)
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- Target: EpCAM
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Anti-EpCAM-sulfo-SPDB-DM4 ADC (ADC-101LZY)
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- Target: EpCAM
- Linker: sulfo-SPDB(sulfo-N-succinimidyl 4-(2-pyridyldithio)butyrate
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Anti-EpCAM (clone MOC31)-hydrazone-Doxorubicin ADC (ADC-149LZY)
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- Target: EpCAM
- Linker: acid-cleavable hydrazone
linker - Drug: Doxorubicin
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.