Mouse Anti-FOLH1 Recombinant Antibody (clone J591) (CAT#: VS-0224-XY49)
Murine mAb J591 (muJ591) was chosen for clinical development as it had been extensively studied in preclinical models, demonstrating that it effectively targets FOLH1 expressed on LNCaP cells. J591 has an affinity of 1 nM which has been shown to be an optimal affinity in therapeutic models.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Kidney
(Proximal tubules (microvilli)
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_7_5.jpg
(Proximal tubules (microvilli)
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_7_5.jpg
Figure 2 Prostate
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_2_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_2_5.jpg
Figure 3 RNA cell line category: Cell line enhanced (HAP1, RPMI-8226, SK-BR-3, TIME, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
Figure 3 RNA cell line category: Cell line enhanced (HAP1, RPMI-8226, SK-BR-3, TIME, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human FOLH1
- Species Reactivity
- Human
- Clone
- J591
- Applications
- Functional assay
- Related Disease
- Hyperhomocysteinemia; Prostate Cancer
Product Property
- Purification
- Protein A or G purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Format
- Liquid
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "FOLH1"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1169z-S(P) | Recombinant Anti-Human FOLH1 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| HPAB-M0614-YC-S(P) | Human Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-M0614-YC-S(P)) | ELISA, FC, Cyt, FuncS | Human scFv |
| HPAB-1248WJ-S(P) | Human Anti-FOLH1 Recombinant Antibody (clone 3D8); scFv Fragment | ELISA | Human scFv |
| HPAB-1249WJ-S(P) | Human Anti-FOLH1 Recombinant Antibody (clone 4D4); scFv Fragment | ELISA | Human scFv |
| HPAB-1250WJ-S(P) | Human Anti-FOLH1 Recombinant Antibody (clone 3E11); scFv Fragment | ELISA | Human scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-066 | Recombinant Anti-Human FOLH1 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-277CT | Anti-Human PSMA Therapeutic Single Domain Single Domain Antibody (TAB-277CT) | ELISA | Single domain antibody |
| HPAB-M0386-YC | Recombinant Camelid Anti-FOLH1 Single Domain Antibody (HPAB-M0386-YC) | ELISA | Camelid VHH |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018 | Anti-Human PMSA Recombinant Antibody (Capromab Pendetide) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG1 - kappa |
| TAB-274CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-274CT) | FC, IA, IHC, Inhib, IB, IF, WB, ELISA | Mouse IgG2a |
| TAB-275CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-275CT) | ICC, FC, Block, IB, IF, IHC, Inhib, WB, ELISA | Mouse IgG1 |
| TAB-276CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-276CT) | IB, FC, IF, Inhib, WB, ELISA, IHC | Mouse IgG2b |
| TAB-274CT-S(P) | Mouse Anti-FOLH1 Recombinant Antibody; scFv Fragment (TAB-274CT-S(P)) | WB, ELISA, FC, IF, IHC | Mouse scFv |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G029E | Anti-FOLH1 immunotoxin D7 (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G029D | Anti-FOLH1 immunotoxin D7 (scFv)-DT | Cytotoxicity assay, Function study |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1332 | Hi-Affi™ Rabbit Anti-FOLH1 Recombinant Antibody (clone DS1332AB) | IHC-P | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0184CQ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone 2A10); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0185CQ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone YC058); Fab Fragment | FC, IHC | Human Fab |
| HPAB-1248WJ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone 3D8); Fab Fragment | ELISA | Human Fab |
| HPAB-1249WJ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone 4D4); Fab Fragment | ELISA | Human Fab |
| HPAB-1250WJ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone 3E11); Fab Fragment | ELISA | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-018 | Afuco™ Anti-FOLH1 ADCC Recombinant Antibody (Capromab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0677 | PE-A*02:01/Human FOLH1 (MMNDQLMFL) MHC Tetramer | FCM, IHC | |
| MHC-CN0678 | APC-A*02:01/Human FOLH1 (MMNDQLMFL) MHC Tetramer | FCM, IHC | |
| MHC-CN0679 | FITC-A*02:01/Human FOLH1 (MMNDQLMFL) MHC Tetramer | FCM, IHC | |
| MHC-CN0680 | A*02:01/Human FOLH1 (MMNDQLMFL) MHC Tetramer | FCM, IHC | |
| MHC-CN0681 | PE-A*02:01/Human FOLH1 (SLFEPPPPG) MHC Tetramer | FCM, IHC |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0213-YC | Mouse Anti-FOLH1 Recombinant Antibody (HPAB-J0213-YC) | ELISA, IHC (0.3µg/mL), FuncS | Mouse IgG |
| HPAB-J0214-YC | Mouse Anti-FOLH1 Recombinant Antibody (HPAB-J0214-YC) | ELISA, IHC (0.3µg/mL) | Mouse IgG |
| MOB-0224F | Mouse Anti-FOLH1 Recombinant Antibody (MOB-0224F) | IHC-P, IF | Mouse IgG |
| MOB-0225F | Mouse Anti-FOLH1 Recombinant Antibody (MOB-0225F) | IHC-P, IF | Mouse IgG |
| VS3-FY558 | Recombinant Mouse Anti-FOLH1 Antibody (clone 5D5-7G4-1B7) | IHC-P | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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