This immunotoxin was achieved by conjugating/fusing the Anti-FOLH1 scFv to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to prostate cancer cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treating prostate cancer.
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• Confirmed specificity
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1169z-S(P) | Recombinant Anti-Human FOLH1 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
HPAB-0656-CN-S(P) | Mouse Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-0656-CN-S(P)) | WB, IF, FC | Mouse scFv |
HPAB-M0614-YC-S(P) | Human Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-M0614-YC-S(P)) | ELISA, FC, Cyt, FuncS | Human scFv |
HPAB-1154WJ-S(P) | Mouse Anti-FOLH1 Recombinant Antibody (clone E99); scFv Fragment | ELISA | Mouse scFv |
HPAB-S0115-YC-S(P) | Human Anti-FOLH1 Recombinant Antibody (clone V5); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-066 | Recombinant Anti-Human FOLH1 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
TAB-277CT | Anti-Human PSMA Therapeutic Single Domain Single Domain Antibody (C3) | ELISA | Single domain antibody |
HPAB-M0386-YC | Recombinant Camelid Anti-FOLH1 Single Domain Antibody (M/YC-1) | ELISA | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G029D | Anti-FOLH1 immunotoxin D7 (scFv)-DT | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-274CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-274CT) | FC, IA, IHC, Inhib, IB, IF, WB, ELISA | Mouse IgG2a |
TAB-275CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-275CT) | ICC, FC, Block, IB, IF, IHC, Inhib, WB, ELISA | Mouse IgG1 |
TAB-276CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-276CT) | IB, FC, IF, Inhib, WB, ELISA, IHC | Mouse IgG2b |
TAB-278CT | Anti-Human PSMA Recombinant Antibody (L-186) | WB, ELISA, IP, IF | |
TAB-279CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-279CT) | FC, WB, ICC, SPR, RIA, IF, ELISA, IHC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0336MZ | Recombinant Mouse Anti-Human FOLH1 Antibody (clone 4F7) | IHC | Mouse antibody |
HPAB-0656-CN | Mouse Anti-FOLH1 Recombinant Antibody (HPAB-0656-CN) | WB, IF, FC | Mouse IgG1 |
HPAB-N0091-YC | Human Anti-FOLH1 Recombinant Antibody (HPAB-N0091-YC) | ELISA, FC, FuncS, Block | Human IgG |
HPAB-N0092-YC | Human Anti-FOLH1 Recombinant Antibody (HPAB-N0092-YC) | ELISA, FC | Human IgG1, κ |
VS3-FY558 | Recombinant Mouse Anti-FOLH1 Antibody (clone 5D5-7G4-1B7) | IHC-P | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1332 | Hi-Affi™ Rabbit Anti-FOLH1 Recombinant Antibody (clone DS1332AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC2502 | PE-B*07:02/Human FOLH1 (LPSIPVHPI) MHC Tetramer | FCM | |
MHC-LC2503 | PE-B*35:01/Human FOLH1 (LPSIPVHPI) MHC Tetramer | FCM | |
MHC-CN0089 | APC-B*27:05/Human PSMA (FRGNKVKNA) MHC Tetramer | FCM | |
MHC-CN0090 | PE-B*27:05/Human PSMA (FRGNKVKNA) MHC Tetramer | FCM | |
MHC-YF277 | A*02:01/Human PSMA (VLAGGFFLL) MHC Monomer | MHC Multimer |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0656-CN-F(E) | Mouse Anti-FOLH1 Recombinant Antibody; Fab Fragment (HPAB-0656-CN-F(E)) | WB, IF, FC | Mouse Fab |
HPAB-0184CQ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone 2A10); Fab Fragment | ELISA, FC | Human Fab |
HPAB-0185CQ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone YC058); Fab Fragment | FC, IHC | Human Fab |
HPAB-N0091-YC-F(E) | Human Anti-FOLH1 Recombinant Antibody; Fab Fragment (HPAB-N0091-YC-F(E)) | ELISA, FC, FuncS, Block | Human Fab |
HPAB-N0092-YC-F(E) | Human Anti-FOLH1 Recombinant Antibody; Fab Fragment (HPAB-N0092-YC-F(E)) | ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-018 | Afuco™ Anti-FOLH1 ADCC Recombinant Antibody (Capromab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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