Human Anti-Phospholipid Recombinant Antibody (clone AH2) (CAT#: FAMAB-0016WJ)
This product is a human antibody developed by fusing the peripheral blood lymphocytes of three patients with SLE with a mouse human heteromyeloma cell line. This antibody binds to a variety of anionic phospholipids, total histones but none binds to ssDNA or dsDNA.
Specific Inquiry
ELISA
Figure 1 Binding curves for AH2 against CL in a standard antiphospholipid antibodies (APL) assay.
CL in a modified assay, histone at 2.5 μg/ml, histone at 1.0 μg/ml.
Menon, S., Rahman, M. A. A., Ravirajan, C. T., Kandiah, D., Longhurst, C. M., McNally, T., ... & Isenberg, D. A. (1997). The production, binding characteristics and sequence analysis of four human IgG monoclonal antiphospholipid antibodies. Journal of autoimmunity, 10(1), 43-57.
ELISA
Figure 2 Inhibition of the binding of monoclonal APL to CL-coated ELISA plates by co-incubation with serial concentrations of CL.
Inhibition of the binding of LJ1, AH2, DA3 and UK4.
Menon, S., Rahman, M. A. A., Ravirajan, C. T., Kandiah, D., Longhurst, C. M., McNally, T., ... & Isenberg, D. A. (1997). The production, binding characteristics and sequence analysis of four human IgG monoclonal antiphospholipid antibodies. Journal of autoimmunity, 10(1), 43-57.
Specifications
- Host Species
- Human
- Type
- Human IgG1, λ
- Specificity
- Phospholipid
- Clone
- AH2
- Applications
- ELISA
- Related Disease
- Systemic lupus erythematosus
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The Phospholipid antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Phospholipid
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone AH2"
See other products for "Phospholipid"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1133-CN | Mouse Anti-Phospholipid Recombinant Antibody (clone C2) | WB, ELISA, IF, IHC, FC | Mouse IgM, κ |
| FAMAB-0015WJ | Human Anti-Phospholipid Recombinant Antibody (clone LJ1) | FC, ELISA | Human IgG3, λ |
| FAMAB-0017WJ | Human Anti-Phospholipid Recombinant Antibody (clone DA3) | ELISA | Human IgG3, λ |
| FAMAB-0098WJ | Human Anti-Phospholipid Recombinant Antibody (clone STO 103) | ELISA, WB | Human IgG |
| FAMAB-0101WJ | Human Anti-Phospholipid Recombinant Antibody (clone BH1) | ELISA | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0015WJ-F(E) | Human Anti-Phospholipid Recombinant Antibody (clone LJ1); Fab Fragment | ELISA, IF | Human Fab |
| FAMAB-0016WJ-F(E) | Human Anti-Phospholipid Recombinant Antibody (clone AH2); Fab Fragment | ELISA, IF | Human Fab |
| FAMAB-0017WJ-F(E) | Human Anti-Phospholipid Recombinant Antibody (clone DA3); Fab Fragment | ELISA, IF | Human Fab |
| FAMAB-0098WJ-F(E) | Human Anti-Phospholipid Recombinant Antibody (clone STO 103); Fab Fragment | ELISA, WB | Human Fab |
| FAMAB-0101WJ-F(E) | Human Anti-Phospholipid Recombinant Antibody (clone BH1); Fab Fragment | ELISA | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0015WJ-S(P) | Human Anti-Phospholipid Recombinant Antibody (clone LJ1); scFv Fragment | ELISA, IF | Human scFv |
| FAMAB-0016WJ-S(P) | Human Anti-Phospholipid Recombinant Antibody (clone AH2); scFv Fragment | ELISA, IF | Human scFv |
| FAMAB-0017WJ-S(P) | Human Anti-Phospholipid Recombinant Antibody (clone DA3); scFv Fragment | ELISA, IF | Human scFv |
| FAMAB-0018WJ-S(P) | Human Anti-Phospholipid Recombinant Antibody (clone UK4); scFv Fragment | ELISA, IF | Human scFv |
| FAMAB-0101WJ-S(P) | Human Anti-Phospholipid Recombinant Antibody (clone BH1); scFv Fragment | ELISA | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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