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The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin.
Protein class


Predicted location


Single cell type specificity

Cell type enhanced (Oligodendrocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity


May form homooligomers and heterooligomers with ADIPOR1 (PubMed:12802337). Interacts with APPL2 (via BAR domain); ADIPOQ dissociates this interaction (By similarity).

Molecular function


More Types Infomation

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