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STXBP1
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor.
Protein class
Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Excitatory neurons, Inhibitory neurons, Cone photoreceptor cells, Rod photoreceptor cells, Bipolar cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (SCLC-21H, SK-MEL-30)
Interaction
Interacts with SYTL4 (By similarity). Interacts with STX1A (PubMed:12730201). Interacts with alpha-synuclein/SNCA; this interaction controls SNCA self-replicating aggregation (PubMed:27597756). Interacts with RAB3A; this interaction promotes RAB3A dissociation from the vesicle membrane (By similarity). Interacts with CABP5 (By similarity).
More Types Infomation
- Recombinant Mouse Anti-Human STXBP1 Antibody (MOB-1164MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP, ICC/IF
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
- Rabbit Anti-STXBP1 Recombinant Antibody (VS-0223-WK48) (VS-0223-WK48)
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- Derivation: Rabbit
- Species Reactivity: Rat, Mouse
- Type: Rabbit IgG
- Application: WB, ICC
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For Research Use Only. Not For Clinical Use.