Specifications

Immunogen
Synthetic peptide of human Munc18-1

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human, Mouse and Rat STXBP1

Species Reactivity
Human, Mouse, Rat

Clone
R05-4B6

Applications
Western Blot

MW
The calculated weight of the target protein is approximately 68 kDa, while the observed molecular weight stands at 68 kDa.

Related Disease
Developmental And Epileptic Encephalopathy 4 and Infantile Epilepsy Syndrome

Product Property

Purification
Affinity Purified

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA

Preservative
0.01% Sodium azide

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
P67; NSEC1; UNC18; RBSEC1; MUNC18-1

Gene ID
6812

UniProt ID
P61764

Sequence Similarities
Belongs to the STXBP/unc-18/SEC1 family.

Cellular Localization
Cytoplasm, Membrane

Post Translation Modifications
Modification sites at PhosphoSitePlus (P61764)
Modification sites at neXtProt (NX_P61764)
Glycosylation from GlyGen (P61764) 1 site, 1 O-linked glycan (1 site)

Protein Refseq
NP_001027392.1; NP_001361235.1; NP_001361236.1; NP_001361237.1; NP_001361238.1

Function
Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity).
Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio.

Recommended Products

Secondary Antibody

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

See other products for "STXBP1"

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IgG Antibody Products Rabbit Monoclonal Antibody Products

CAT	Product Name	Application	Type
MOB-1164MZ	Recombinant Mouse Anti-Human STXBP1 Antibody	IHC-P, WB	Mouse antibody
VS-0223-WK48	Rabbit Anti-STXBP1 Recombinant Antibody (VS-0223-WK48)	WB, ICC	Rabbit IgG

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