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TCEA1

TCEA1 (Transcription Elongation Factor A1) is a Protein Coding gene. Diseases associated with TCEA1 include Cockayne Syndrome. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and Transcription-Coupled Nucleotide Excision Repair (TC-NER). Gene Ontology (GO) annotations related to this gene include nucleic acid binding and translation elongation factor activity. An important paralog of this gene is TCEA2.
Protein class

Cancer-related genes, Disease related genes

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with EAF2 (By similarity). Associates with UBR5 and forms a transcription regulatory complex made of CDK9, RNAP II, UBR5 and TFIIS/TCEA1 that can stimulate target gene transcription (e. g. gamma fibrinogen/FGG) by recruiting their promoters.

Molecular function

DNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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