Anti-HIV-1 antibody is a Human antibody of IgG class that binds to an HIV-1.
Figure 1 Binding kinetics for BG505.SOSIP and 15-sc gp140 with VRC26.09 and PGT145.
Georgiev, I. S., Joyce, M. G., Yang, Y., Sastry, M., Zhang, B., Baxa, U., ... & Schön, A. (2015). Single-chain soluble BG505. SOSIP gp140 trimers as structural and antigenic mimics of mature closed HIV-1 Env. Journal of virology, 89(10), 5318-5329.
Figure 2 Binding of SOSIP and SOSIP-sfGFP proteins in HEK293T cell supernatant to bNAbs 2G12 and PGT145 as assessed by ELISA.
SOSIP and SOSIP-sfGFP proteins were captured onto the solid phase.
Sliepen, K., Van Montfort, T., Ozorowski, G., Pritchard, L., Crispin, M., Ward, A., & Sanders, R. (2015). Engineering and characterization of a fluorescent native-like HIV-1 envelope glycoprotein trimer. Biomolecules, 5(4), 2919-2934.
Figure 3 Coomassie-stained reducing and non-reducing SDS-PAGE gels showing SOSIP and SOSIP-sfGFP, both purified with a PGT145-affinity column.
Sliepen, K., Van Montfort, T., Ozorowski, G., Pritchard, L., Crispin, M., Ward, A., & Sanders, R. (2015). Engineering and characterization of a fluorescent native-like HIV-1 envelope glycoprotein trimer. Biomolecules, 5(4), 2919-2934.
Figure 4 Antigenicity characterization by ECLIA. An extended panel of both broadly and poorly neutralizing antibodies was assessed using ECLIA for cleaved (black open circles) and 15-sc gp140 (red filled circles) BG505.SOSIP constructs.
Sliepen, K., Van Montfort, T., Ozorowski, G., Pritchard, L., Crispin, M., Ward, A., & Sanders, R. (2015). Engineering and characterization of a fluorescent native-like HIV-1 envelope glycoprotein trimer. Biomolecules, 5(4), 2919-2934.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-380 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC06) | FC, Neut, FuncS | Human IgG |
PABW-060 | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 58.2) | Neut | Mouse IgG1 |
PABC-061 | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 83.1) | Neut | Mouse IgG1 |
PABZ-061 | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 0.5β) | Neut | Mouse IgG |
PABC-062 | Recombinant Human Anti-HIV-1 gp120 Antibody (2G12) | Neut, ELISA | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91C2) | ELISA | Single domain antibody |
MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91F10) | ELISA | Single domain antibody |
MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91E1) | ELISA | Single domain antibody |
MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91B5) | ELISA | Single domain antibody |
MRO-032LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91H9) | ELISA | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-041LC | Anti-HIV-1 gp120 Recombinant Antibody (D59/A2) | ELISA | Mouse antibody |
MRO-042LC | Anti-HIV-1 gp120 Recombinant Antibody (F58/H3) | WB, ELISA | Mouse antibody |
MRO-043LC | Anti-HIV-1 gp120 Recombinant Antibody (P1/D12) | ELISA | Mouse antibody |
MRO-044LC | Anti-HIV-1 gp120 Recombinant Antibody (P4/D10) | ELISA | Mouse antibody |
MRO-045LC | Anti-HIV-1 gp120 Recombinant Antibody (A47/B1) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-125LC | Anti-HIV-1 gp120 Recombinant Antibody (N6) | Neut, ELISA | Human antibody |
MRO-130LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-130LC) | ELISA, Neut, SPR | Human IgG |
MRO-136LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900973) | ELISA | Human antibody |
MRO-137LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900972) | ELISA | Human antibody |
MRO-138LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900990) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-3224CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone N5-i2); Fab Fragment | Neut, ELISA | Human Fab |
MRO-3225CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone N5-i3); Fab Fragment | Neut, ELISA | Human Fab |
MRO-3226CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone N5-i4); Fab Fragment | Neut, ELISA | Human Fab |
MRO-3227CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone N5-i6); Fab Fragment | Neut, ELISA | Human Fab |
MRO-3228CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone N5-i7); Fab Fragment | Neut, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0202CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone CAP228-16H); scFv Fragment | ELISA, Neut | Human scFv |
PSBC-291 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1A8); scFv Fragment | Neut | Human scFv |
HPAB-0079-WJ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone B12); scFv Fragment | ELISA, Neut | Mouse scFv |
HPAB-S0049-YC-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 4022); scFv Fragment | ELISA | Human scFv |
HPAB-S0050-YC-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 3792); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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