Recombinant Mouse Antibody (0. 5β) is capable of binding to HIV-1 gp120, expressed in mammalian cells. The affinity of 0. 5β for the V3 peptide P1053 (RKSIRIQRGPGRAFVTIG) was found to be comparable to its affinity for the intact glycoprotein.
Figure 1 Titration of the 0.5β Fv fragment with wild-type peptide monitored by fluorescence enhancement.
The concentration of the 0.5β Fv fragment was 0.5 μM.
Faiman, G. A., Levy, R., Anglister, J., & Horovitz, A. (1996). Contribution of Arginine Residues in the RP135 Peptide Derived from the V3 Loop of gp120 to Its Interaction with the Fv Fragment of the 0.5 β HIV-1 Neutralizing Antibody. Journal of Biological Chemistry, 271(23), 13829-13833.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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PABL-520 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 44-VRC13.01) | Neut | Human IgG |
PABL-521 | Human Anti-HIV-1 gp120 Recombinant Antibody (PABL-521) | ELISA, Neut | Human IgG |
PABL-522 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 45-VRC01.H5.F-185917) | WB, FuncS | Human IgG |
PABL-523 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 8ANC131) | WB, FuncS | Human IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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