Monkey Anti-HIV-1 gp120 Recombinant Antibody (clone 1.8E) (CAT#: MRO-3534CQ)

Recombinant Macaque Antibody to gp120. 1.8E showed potent neutralizing activity against the homologous virus (SF162) but not heterologous viruses. 1.8E recognizes a complex quaternary structure present on the Env spikes.


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Neut

Figure 1 HIV-1 SF162 neutralization susceptibility by RhMAbs.

Figure 1 HIV-1 SF162 neutralization susceptibility by RhMAbs.

The neutralizing activity of the RhMAbs against HIV-1 SF162 was determined using the TZM-bl pseudovirus neutralization assay.

Robinson, J. E., Franco, K., Elliott, D., Maher, M. J., Reyna, A. A., Montefiori, D. C., ... & Stamatatos, L. (2010). Quaternary Epitope Specificities of Anti-HIV-1 Neutralizing Antibodies Generated in Rhesus Macaques Infected by the Simian/Human Immunodeficiency Virus SHIVSF162P4. Journal of Virology, 84(7), 3443-3453.


Specifications

  • Immunogen
  • SF162
  • Host Species
  • Monkey
  • Type
  • Monkey IgG
  • Specificity
  • Recognizes HIV-1 gp120
  • Species Reactivity
  • HIV-1
  • Clone
  • 1.8E
  • Applications
  • Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Neutralization Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 1.8E"

See other products for "HIV-1 gp120"

Single-domain Antibody

Mouse Antibody

CAT Product Name Application Type
MRO-132LC Anti-HIV-1 gp120 Recombinant Antibody (BAT123) ELISA, WB, IF, Neut Mouse antibody
MRO-133LC Anti-HIV-1 gp120 Recombinant Antibody (BAT267) ELISA, WB, Neut Mouse antibody
MRO-134LC Anti-HIV-1 gp120 Recombinant Antibody (BAT085) ELISA, WB, IF, Neut Mouse antibody
MRO-150LC Anti-HIV-1 gp120 Recombinant Antibody (G3-4) ELISA, Inhib, FC, Neut, RIPA, DB, IP Mouse antibody
MRO-152LC Anti-HIV-1 gp120 Recombinant Antibody (G3-136) Neut, ELISA Mouse antibody

Chimeric Antibody

CAT Product Name Application Type
MRO-135LC Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) ELISA, WB, Neut Chimeric antibody (mouse/human)
MRO-135LC-S(P) Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)
MRO-135LC-F(E) Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4220 Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) WB, ELISA Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
PABX-101-S(P) Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment WB, ELISA, FuncS Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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