Loading...
ATP12A
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene.
Protein class
Enzymes, Metabolic proteins, Plasma proteins, Transporters
Predicted location
Membrane
Single cell type specificity
Group enriched (Basal respiratory cells, Club cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (SuSa)
Interaction
The ATPase pump is composed of a catalytic alpha subunit and an auxiliary non-catalytic beta subunit. The alpha subunit pairs with the beta subunit of gastric H(+)/K(+) ATPase ATP4B or the beta subunit of Na(+)/K(+) ATPases ATP1B1 and ATP1B3; this interaction is required for the formation of a functionally active pump and its targeting at the plasma membrane.
Molecular function
Translocase
More Types Infomation
Related Signaling Pathways
cAMP Signaling Pathway
Related Diseases
Morphine Addiction
- Recombinant Anti-Human ATP12A Antibody (MOB-2970z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, Dot, FuncS
- Mouse Anti-Human ATP12A Polyclonal Antibody (MOB-005CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB
- Recombinant Anti-Human ATP12A Antibody scFv Fragment (MOB-2970z-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, IP, FuncS
- Recombinant Anti-Human ATP12A Antibody Fab Fragment (MOB-2970z-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, Neut, FuncS
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.