GAD2
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1
Application: WB, ELISA, FC
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Species Reactivity: Human
Type: Mouse IgG
Application: ELISA, ICC, IHC, FC, WB
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Species Reactivity: Human, Mouse, Rat, Canine, Pig
Application: WB
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Derivation: Phage display library
Species Reactivity: Human
Type: Rabbit IgG
Application: WB
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Species Reactivity: Rat
Type: Mouse antibody
Application: IHC-FoFr, IHC-Fr, IHC-P, WB
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Species Reactivity: Human
Epitope: NMYAMMIARFKMFPEVKEKG
MHC: HLA-DR
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Species Reactivity: Human
Epitope: NMYAMMIARFKMFPEVKEKG
MHC: HLA-DR
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Species Reactivity: Human
Type: Rabbit IgG
Application: ELISA
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Species Reactivity: Human
Type: Rabbit IgG
Application: ELISA
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Derivation: Rabbit
Species Reactivity: Rat, Mouse
Type: Rabbit IgG
Application: WB, ICC, IHC
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Derivation: Human
Species Reactivity: Human
Type: ADCC enhanced antibody
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Derivation: Mouse
Species Reactivity: Human, Rat
Type: Mouse IgG1
Application: WB
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1
Application: WB, ELISA
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Species Reactivity: Human
Type: Human Fab, λ
Application: Inhib
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Derivation: Mouse
Species Reactivity: Human, Rat
Type: Mouse IgG2b
Application: WB
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Derivation: Mouse
Species Reactivity: Human, Mouse, Rat
Type: Mouse IgG1
Application: WB
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Species Reactivity: Human
Type: Human IgG1, λ
Application: Inhib
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Species Reactivity: Mouse, Rat, Human
Type: Mouse IgG1
Application: WB, FC, IP
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Derivation: Human
Species Reactivity: Human
Type: Antibody
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Species Reactivity: Human
Type: Human scFv
Application: Inhib
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For Research Use Only. Not For Clinical Use.