This product is a recombinant antibody that recognizes Human ERBB3. The monoclonal antibody 15D5 reacts with the epitope of ERBB3. The anti-HER3 15D5 antibodies inhibited heregulin induced HER3 phosphorylation in the BxPC3.
Figure 1 Inhibition of heregulin induced human HER3 receptor phosphorylation with anti-HER3 antibodies in BxPC3 pancreatic cancer cells.
Figure 2 The murine 15D5 antibody (M5.15D5.1C1) cross-reacts with murine HER3 expressed on B16F10 cells.
Figure 3 The murine 1D9 antibody (M5.1D9.1F5), the murine 15D5 antibody (M5.15D5.2A1), the murine24H5 antibody (M5.24H5.C2), the chimeric 1D9 antibody and the chimeric 15D5 antibody inhibit heregulin induced BxPC3 pancreatic cancer cell invasion.
Figure 4 The murine 15D5 antibody (M5.15D5.2A1.H10) and humanized 1D9 antibody induced receptor internalization in human CHL-1 melanoma cells.
Figure 5 Efficacy of mouse anti-HER3 mAb, murine 1D9 antibody, in the B 16F10 syngeneic tumor model.
Figure 6 Efficacy of mouse anti-HER3 mAb, murine 15D5 antibody, in the CHL-1 xenograft model.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1729-sdAb | Recombinant Anti-human ERBB3 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
TAB-070CT | Llama Anti-ERBB3 Recombinant Single Domain Antibody (TAB-070CT) | FC, Block | Llama VHH |
PABC-556 | Recombinant Llama Anti-ERBB3 Single Domain Antibody (PABC-556) | ELISA, SPR | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L074E | HRGβ2-PE immunotoxin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-086 | Human Anti-ERBB3 Recombinant Antibody (clone KTN3379) | ELISA, WB, IF, FuncS | Human IgG |
HPAB-0022-WJ | Human Anti-ERBB3 Recombinant Antibody (HPAB-0022-WJ) | ELISA, Inhib, WB, FuncS | Human IgG1, λ |
HPAB-0024-WJ | Human Anti-ERBB3 Recombinant Antibody (HPAB-0024-WJ) | ELISA | Human IgG1 |
HPAB-0025-WJ | Human Anti-ERBB3 Recombinant Antibody (HPAB-0025-WJ) | ELISA | Human IgG1 |
HPAB-0220-FY | Human Anti-ERBB3 Recombinant Antibody (clone Hu-E14) | ELISA, WB | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-086 | Human Anti-ERBB3 Recombinant Antibody (clone KTN3379); scFv Fragment | ELISA, WB, IF, FuncS | Human scFv |
HPAB-0608-WJ-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (HPAB-0608-WJ-S(P)) | ELISA, IHC | Humanized scFv |
HPAB-0609-WJ-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (HPAB-0609-WJ-S(P)) | ELISA, IHC | Humanized scFv |
HPAB-1695-FY-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-1695-FY-F(E)) | ELISA | Human Fab |
HPAB-1696-FY-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-1696-FY-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0048CL-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-0048CL-F(E)) | ELISA, FuncS, Inhib, FC | Human Fab |
TAB-0049CL-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-0049CL-F(E)) | ELISA, FuncS, Inhib, FC | Human Fab |
TAB-0050CL-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-0050CL-F(E)) | ELISA, FuncS, Inhib, FC | Human Fab |
TAB-065CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-065CT-F(E)) | ELISA, FC | Human Fab |
TAB-066CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-066CT-F(E)) | ELISA, Inhibion, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0508CL-F(E) | Anti-Human ERBB3 Recombinant Antibody Fab Fragment (1A5) | ELISA, Inhib, FuncS | |
TAB-0509CL-F(E) | Anti-Human ERBB3 Recombinant Antibody Fab Fragment (3D4) | ELISA, Inhib, FuncS | |
TAB-060CT | Rabbit Anti-ERBB3 Recombinant Antibody (TAB-060CT) | Inhib, ELISA | Rabbit IgG |
TAB-064CT-S(P) | Mouse Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-064CT-S(P)) | ELISA, FC | Mouse scFv |
TAB-067CT-S(P) | Anti-Human HER3 Recombinant Antibody scFv Fragment (5101) | ELISA, Inhibition, FC |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-061CT | Human Anti-ERBB3 Recombinant Antibody (TAB-061CT) | Inhib, ELISA | Chimeric (Rabbit/Human) antibody |
TAB-061CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-061CT-S(P)) | Inhib, ELISA | Human scFv |
TAB-061CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-061CT-F(E)) | Inhib, ELISA | Chimeric (Rabbit/Human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-063CT | Human Anti-ERBB3 Recombinant Antibody (TAB-063CT) | IF, WB, Inhib, ELISA | Humanized antibody |
TAB-057CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-057CT-S(P)) | Inhibion, ELISA | Humanized scFv |
TAB-058CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-058CT-S(P)) | WB, ELISA, Inhib | Human scFv |
TAB-059CT-S(P) | Anti-Human HER3 Recombinant Antibody scFv Fragment (LMAb3) | WB, ELISA, Inhibition, FC | Humanized antibody |
TAB-057CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-057CT-F(E)) | Inhibion, ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-738CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL932) | Neut, IP | Mouse IgG1 |
NEUT-739CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL483) | FC, CyTOF®, ELISA, Neut | Mouse IgG1 |
NEUT-740CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1019) | Neut | Human IgG1, κ |
NEUT-741CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1020) | Neut | Human IgG1, κ |
NEUT-742CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone M908) | Neut | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1179 | Hi-Affi™ Rabbit Anti-ERBB3 Recombinant Antibody (clone DS1179AB) | ICC, IF, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0286-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 1153); Fab Fragment | ELISA, FuncS, FC | Mouse Fab |
HPAB-0287-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 920104); Fab Fragment | ELISA, FuncS, FC | Mouse Fab |
HPAB-0288-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 1126); Fab Fragment | ELISA, FuncS, FC | Mouse Fab |
HPAB-0289-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 12511); Fab Fragment | ELISA, FuncS, FC | Mouse Fab |
HPAB-0290-YC-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0290-YC-F(E)) | ELISA, FuncS, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H21 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-422CQ | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Elgemtumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
AFC-TAB-189 | Afuco™ Anti-ERBB3 Recombinant Antibody (AFC-TAB-189), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | Human IgG1, κ |
AFC-TAB-H22 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotuzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-892 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Seribantumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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