Recombinant Llama Anti-ERBB3 Single Domain Antibody (PABC-556) (CAT#: PABC-556)
This product is a recombinant Llama antibody that can recognize ErbB3. BCD090-M2 recognises erbB3, a receptor tyrosine kinase.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SPR
Figure 1 Binding of BCD090-M2 VHH antibody to the extracellular domain of human ErbB3 receptor analyzed by surface plasmon resonance.
Eliseev, I. E., Yudenko, A. N., Vysochinskaya, V. V., Svirina, A. A., Evstratyeva, A. V., Drozhzhachih, M. S., ... & Ulitin, A. B. (2018). Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor. F1000Research, 7.
SPR
Figure 2 Binding of BCD090-M2 VHH antibody to the extracellular domain of human ErbB3 receptor analyzed by surface plasmon resonance.
Fitting of the measured response as a function of concentration of free BCD090-M2 in solution with a simple bimolecular equilibrium binding model gives KD=1 μM.
Eliseev, I. E., Yudenko, A. N., Vysochinskaya, V. V., Svirina, A. A., Evstratyeva, A. V., Drozhzhachih, M. S., ... & Ulitin, A. B. (2018). Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor. F1000Research, 7.
Specifications
- Host Species
- Llama
- Type
- Llama VHH
- Specificity
- Human ErbB3
- Species Reactivity
- Human
- Clone
- PABC-556
- Applications
- ELISA, SPR
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Surface Plasmon Resonance and Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- Erb-B2 Receptor Tyrosine Kinase 3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; Tyrosine Kinase-Type Cell Surface Receptor HER3; Human Epidermal Growth Factor Receptor 3; Proto-Oncogene-Like Protein C-ErbB-3; EC 2.7.10.1; HER3; Lethal Congenital Contracture Syndrome 2; P180-ErbB3; P45-SErbB3; P85-SErbB3; EC 2.7.10; MDA-BF-1; C-ErbB-3; C-ErbB3; ErbB3-S; ErbB-3; LCCS2
- Gene ID
- 2065
- UniProt ID
- P21860
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1729-sdAb | Recombinant Anti-human ERBB3 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| TAB-070CT | Llama Anti-ERBB3 Recombinant Single Domain Antibody (TAB-070CT) | FC, Block | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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