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ACAT1
Loading...Anti-ACAT1 Products
- Anti-ACAT1 Immunohistochemistry Kit (VS-0325-XY18)
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- Species Reactivity: Human, Mouse, Rat
- Target: ACAT1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal tubular cells, Distal tubular cells, Hepatocytes, Cardiomyocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (RPMI-8226)
Interaction
Homotetramer.
Molecular function
Acyltransferase, Transferase
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