Bacterial Immune System Protein Specific Antibody Products

Overview

Featured Targets

• OmpA (Outer Membrane Protein A)

OmpA is one of the most abundant outer membrane proteins in Gram-negative bacteria, playing vital roles in bacterial adhesion, biofilm formation, and resistance to complement-mediated killing. Antibodies against OmpA are widely used in bacterial pathogenesis research, immune detection assays, and studies on antibiotic resistance mechanisms.

• OspA (Outer Surface Protein A)

OspA, a surface lipoprotein from Borrelia burgdorferi, is highly immunogenic and crucial for bacterial survival in the tick vector. Anti-OspA antibodies are essential for Lyme disease diagnostics and vaccine research, as OspA is one of the earliest and most characterized immune targets in Borrelia.

• OspB (Outer Surface Protein B)

OspB is another major Borrelia surface antigen that functions in host–vector transmission and immune evasion. Our OspB antibodies are ideal for studying bacterial surface protein dynamics, serological detection, and immune response profiling in Lyme disease and related spirochetal infections.

• VlsE (Variable Major Protein-Like Sequence Expressed)

VlsE is a critical antigenic variation protein that enables Borrelia burgdorferi to escape host immune surveillance during persistent infection. Antibodies targeting VlsE are valuable tools for serodiagnosis, immune monitoring, and understanding the molecular mechanisms of bacterial antigenic variation.

Applications

Our antibodies are validated and optimized for a range of experimental platforms, including:

• Western Blot (WB): Protein expression and identity verification.
• ELISA: Quantitative detection in serum or lysate samples.
• Immunohistochemistry (IHC) and Immunofluorescence (IF): Visualization of bacterial antigens in infected tissues or cells.
• Flow Cytometry (FC): Surface antigen detection and immune profiling.
• Vaccine Research: Screening and characterization of candidate antigens.

Advantages of Our Antibodies

• High Specificity & Affinity: Precisely recognize target epitopes on bacterial immune proteins.
• Comprehensive Validation: Each antibody is tested in multiple applications for consistent performance.
• Reproducible and Reliable: Manufactured under strict quality control for batch-to-batch consistency.
• Cross-Species Reactivity Information: Detailed reactivity data available for human, mouse, and bacterial samples.
• Custom Conjugation & Labeling Options: Available in biotin, HRP, FITC and PE-labeled forms.

Supporting Bacterial Immunology and Infectious Disease Research

Understanding bacterial immune targets such as OmpA, OspA, OspB, and VlsE is crucial for developing next-generation vaccines, therapeutic antibodies, and diagnostics. Our antibodies support diverse research fields including:

• Pathogenesis and Host–Pathogen Interaction Studies
• Vaccine Antigen Screening and Validation
• Lyme Disease and Gram-Negative Infection Diagnostics
• Antigenic Variation and Immune Escape Mechanism Analysis

With our comprehensive portfolio and technical expertise, we help researchers achieve deeper insight into bacterial immune systems and translational infectious disease biology.

Partner With Us

Our antibodies against OmpA, OspA, OspB, and VlsE deliver sensitivity, and reliability for every stage of bacterial immunology research. Whether you are investigating bacterial immune evasion, developing diagnostic assays, or designing vaccine candidates, our reagents can help accelerate your discoveries.

Contact us today to explore our Bacterial Immune Target Antibody portfolio or request customized antibody solutions for your research.

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For Research Use Only. Not For Clinical Use.