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CK8
Loading...Anti-CK8 Products
- Human Anti-CK8 Recombinant Antibody (HPAB-0398-FY) (HPAB-0398-FY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA
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- Human Anti-CK8 Recombinant Antibody; scFv Fragment (HPAB-0398-FY-S(P)) (HPAB-0398-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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- Human Anti-CK8 Recombinant Antibody; Fab Fragment (HPAB-0398-FY-F(E)) (HPAB-0398-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Anti-CK8 Immunohistochemistry Kit (VS-0325-XY459)
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- Species Reactivity: Human, Mouse, Rat
- Target: CK8
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Keratin 8 (KRT8) is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
