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FGFR1c
Loading...Anti-FGFR1c Products
- Human Anti-FGFR1c Recombinant Antibody (clone AP009/YC) (HPAB-AP653-YC)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib
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- Human Anti-FGFR1c Recombinant Antibody (clone AP009/YC); scFv Fragment (HPAB-AP653-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Inhib
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- Human Anti-FGFR1c Recombinant Antibody (clone AP009/YC); Fab Fragment (HPAB-AP653-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Inhib
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For Research Use Only. Not For Clinical Use.
Background
Fibroblast Growth Factor Receptors (FGFRs) 1-5 have common structural features which consist of an extracellular ligand-binding section composed of three domains (Ig domains I, II, and III), a transmembrane domain, and an intracellular tyrosine kinase catalytic domain. At least 22 ligands (FGFs) are known that signal through FGFRs 1-5. In FGFR-1 alternative splicing of the exon encoding the third IgG-like domain produces the b- or c-splice form both of which have distinct ligand-binding preferences. The FGFR1c splice form has been shown to regulate food intake.
