APC-H-2Db/Human Survivin (ATFKNWPFL) MHC Tetramer
CAT#: MHC-LC089
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of Survivin-derived peptide of ATFKNWPFL sequence covering 20-28 and H-2Db molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytokinetic bridge.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4270/if_selected.jpg
Normal Tissue
Figure 2 Testis
Pachytene spermatocytes
Staining:High
Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Round or early spermatids
Staining:High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4270/11491_A_6_6.jpg
Normal Tissue
Figure 3 Bone marrow
Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4270/11701_B_4_4.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4270/11491_A_8_8.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000089685-BIRC5
❮
❯
Specifications
- Allele
- H-2Db
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Survivin
- Antigen Species
- Human
- Peptide
- ATFKNWPFL
- Range
- 20-28
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Alternative Names
- BIRC5; baculoviral IAP repeat containing 5; API4; EPR-1; Survivin
- Gene ID
- 332
- UniProt ID
- O15392
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for MHC-LC089. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "BIRC5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-161-VHH | Recombinant Anti-human BIRC5 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1374z | Mouse Anti-BIRC5 Recombinant Antibody (clone 23C5) | ELISA, FC, ICC, IF, IHC, WB | Mouse IgG1 |
| MOB-0339MZ | Mouse Anti-BIRC5 Recombinant Antibody (clone 15D5) | IHC | Mouse IgG2a |
| ZG-0049U | Rabbit Anti-BIRC5 Recombinant Antibody (clone 6G11) | ELISA, IHC | Rabbit IgG |
| VS3-XY122 | Mouse Anti-BIRC5 Recombinant Antibody (clone 1H5) | ELISA, WB, IHC, FC, ICC | Mouse IgG1 |
| VS4-WK49 | Mouse Anti-BIRC5 Recombinant Antibody (VS4-WK49) | ELISA, WB, IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-045CQ | Mouse Anti-BIRC5 Recombinant Antibody (clone 8E2) | WB, Neut, ELISA, FC, IF, IHC, IHC-P | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0360 | Hi-Affi™ Rabbit Anti-BIRC5 Recombinant Antibody (clone DS360AB) | FC, ICC, IHC-P, IP, WB, sELISA | Rabbit IgG |
| MOR-4746 | Hi-Affi™ Rabbit Anti-BIRC5 Recombinant Antibody (clone TH260DS) | WB, IF, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY775 | Anti-BIRC5 Immunohistochemistry Kit | IHC | |
| VS-0525-XY776 | Anti-Mouse BIRC5 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, IHC, FC, WB, IF, IA
Application: WB, ELISA, IF, FuncS, Apop, BA
Application: ELISA, WB, FC, IHC, IP
Application: ELISA, Neut
Application: ELISA, Block, WB, FC, IP
Application: ELISA, IHC, IF, IP
Application: ELISA, FC, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
